NodThera Announces Appointment of Dr. Jyothis George as Chief Medical Officer
Former Amgen, Novo Nordisk and Boehringer Ingelheim senior leader joins NodThera Leadership Team
NodThera, a leading clinical-stage biotech delivering a paradigm shift in the treatment of chronic inflammatory diseases through selective modulation of the NLRP3 inflammasome, announces the appointment of Dr. Jyothis George, M.D., Ph.D., FRCP, FACE as Chief Medical Officer, effective immediately.
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Jyothis brings a wealth of global leadership experience in cardiometabolic drug development, regulatory strategy and medical affairs. He joins NodThera from Amgen, where he served as Global Medical Vice President, Obesity and Related Conditions, driving strategic decision making on target indications and priority patient populations, securing investment to generate differentiating evidence and leading expert engagement. His recent responsibilities included strategic planning around MariTide, Amgen’s lead candidate in obesity.
Previously, Jyothis held leadership roles at Novo Nordisk and Boehringer Ingelheim, directing pivotal programs in obesity, diabetes, heart failure and chronic kidney disease. At Novo Nordisk, Jyothis was Corporate Vice President, Clinical Development, Medical Affairs and Regulatory. There he successfully delivered multiple key clinical trials across the Novo Nordisk portfolio, including major regulatory studies for several assets including semaglutide and launching impactful educational platforms such as ObesityME and the Diabetes Masters Network. At Boehringer Ingelheim, as Global Head of Clinical Development and Medical Affairs, Cardiometabolism, he led the clinical development and medical affairs teams for two blockbuster cardiometabolic assets: empagliflozin, the first diabetes treatment to gain an FDA cardiovascular mortality indication, and the DPP4 inhibitor linagliptin. During his tenure, he successfully delivered multiple global clinical trials, including serving on steering committees of six major cardiovascular outcomes trials.
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Daniel Swisher, Chief Executive Officer of NodThera, said: “We are thrilled to welcome Jyothis to NodThera as our Chief Medical Officer. He brings a critical combination of deep clinical and patient insight coupled to recent global leadership in cardiometabolic drug development, shaping landmark trials and delivering regulatory success. His expertise will be invaluable to NodThera as we advance our brain-penetrant NLRP3 inflammasome inhibitors further through clinical development.”
Jyothis George, M.D., Ph.D., FRCP, FACE, commented: “Joining NodThera provides an exciting opportunity to transform the treatment of diseases driven by chronic low-grade inflammation. I am inspired by the science and the team’s bold vision to reimagine what’s possible for patients by restoring the body’s natural metabolic balance. Together with the team, I am looking forward to building on NodThera’s promising clinical momentum to deliver therapies that are not only differentiated, but truly transformative for patients.”
Jyothis holds an M.B.B.S. from St. John’s Medical College in Bangalore, India; a Ph.D. in Neuroendocrinology from the University of Edinburgh, and is board certified in Internal Medicine, Endocrinology and Diabetes (UK). He is a Fellow of the Royal College of Physicians (Edinburgh) and the American College of Endocrinology and has authored more than 100 peer-reviewed publications. He has previously served on the boards of Amgen Technologies Ireland and Oxford Centre for Diabetes, Endocrinology and Metabolism.
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Source- GlobalNewswire
