The Fund Will be Managed by Experienced Life Sciences Investor Nishant Rastogi
The Lupus Research Alliance, the world’s largest private funder of lupus research, announced the formation of a new philanthropic venture fund Lupus Ventures. The Fund is dedicated to advancing treatments and diagnostics for systemic lupus erythematosus (SLE), its manifestations, and related autoimmune conditions.
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Lupus is a chronic, complex autoimmune disease that affects millions of people worldwide. Treatment development stagnated for years after the U.S. Food and Drug Administration approved Benlysta in 2011. However, with the approvals of Saphnelo and Lupkynis in 2021, and Gazyva in October 2025, the tides are turning. Innovative treatments like engineered cell therapies are showing great promise, and there are over 140 lupus therapies in clinical trials from more than 120 companies.
With that promise, philanthropic investment in higher-risk, early-stage companies is increasingly powerful. Lupus Ventures aims to bridge the gap between innovative science and commercial reality.
“The Lupus Research Alliance has spent years building a research engine that supports every part of the scientific process — from basic and translational research through clinical development,” Albert T. Roy, President & CEO of the Lupus Research Alliance, said. “Launching Lupus Ventures is the natural — and critical — next step. It allows us to strategically deploy resources and catalyze solutions for people living with lupus, ensuring promising ideas don’t sit on a shelf simply for lack of funding.”
Nishant Rastogi will serve as the Fund’s inaugural Managing Director. Mr. Rastogi is an accomplished life sciences investor with more than a decade of biotech venture capital and private equity experience. He has served as a Board Director and operating partner for multiple biotech and medtech companies throughout his career.
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Before joining Lupus Ventures, Mr. Rastogi served as Vice President and Head of Transactions at New Rhein Healthcare Investors. He played an integral role in all aspects of the firm’s evolution and growth — including investment activities, portfolio management, team building, and operations. He was involved in New Rhein’s investments in Corsair (Director), Theranica, Alveus, American Injectables, Butterfly Medical, Softhale (acquired), Neuraptive, and others. Earlier in his career, Mr. Rastogi was an investor at Broadview Ventures and an analyst at Fidelity Investments. He has advised several disease research foundations — including Beyond Celiac, 90/10 Institute, and Parent Project Muscular Dystrophy — on venture fund formation and the role of philanthropy and private investment in advancing new medicines and health equity. Mr. Rastogi earned his BA from Dartmouth College and his MBA from Northwestern University.
“I am grateful to the Lupus Research Alliance for the opportunity to build this platform,” Mr. Rastogi said. “As the world’s only investment fund dedicated to SLE, we are uniquely positioned to support companies developing potential therapies in this area to benefit people living with lupus globally. The combination of recent scientific advancements and investor and industry interest makes this a perfect time to launch the Fund.”
All companies — regardless of modality or stage of development — are being considered for investment. In addition to capital, the companies will also receive counsel and guidance, leveraging the Lupus Research Alliance’s depth of knowledge gained through its industry leadership. To date, the Lupus Research Alliance has awarded more than $284 million across 650+ research grants, and clinical affiliate Lupus Therapeutics is involved in 25-30% of active clinical trials.
The Fund will be overseen by the Investment Committee that includes Mr. Rastogi, Mr. Roy and Ira Akselrad, President and CEO of The Johnson Company, Inc. and Chair of the Lupus Research Alliance Board of Directors. Teodora Staeva, PhD, Chief Scientific Officer of the Lupus Research Alliance, will serve on its Scientific Advisory Board. The Fund plans to recruit additional experts to the Investment Committee, Scientific Advisory Board, and investment team in 2026.
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Source- PR Newswire
