The market for continuous renal replacement therapy was valued at USD 1.5 billion in 2023–2024 and is expected to reach USD 2 billion by 2030, growing at a compound annual growth rate (CAGR) of 7-8 percent. The use of CRRT in the treatment of critically ill patients has grown dramatically as a result of the rapid advancement of technology and the launch of novel products. By creating solutions suited to particular patient demographics, such as pediatric patients, market participants are actively responding to the changing demand for CRRT products. To address cases of fluid overload or AKI, Medtronic, for example, introduced the Carpediem cardio-renal pediatric dialysis emergency machine in December 2020. This machine is intended for pediatric and neonatal patients weighing between 2 and 5 to 10 kilograms. The quality of patient care is improved by developments in membrane technology, customized CRRT delivery, and the incorporation of data analytics in therapy administration and prescription automation, all of which eventually increase the market’s size.
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The largest share during the 2024–2030 forecast period was held by the systems segment. Healthcare practitioners can keep a close eye on important parameters thanks to CRRT systems. Their design allows for flexibility in patient care settings by being either stationary or portable. In 2023, the market for continuous renal replacement therapy was dominated by the CVVHDF segment. By combining hemodialysis and hemofiltration, CVVHDF offers a comprehensive approach to renal replacement therapy and efficiently eliminates waste materials and extra fluid. Additionally, it enables accurate fluid balance control, which makes it especially appropriate for patients who need strict fluid management or who have fluid overload.
The adult segment is anticipated to witness significant growth during the forecast period 2023-2030. CRRT is widely employed in adult populations, particularly in ICUs, where critically ill patients experience AKI or other renal complications. Its continuous and gradual nature makes it well-suited for managing hemodynamically unstable adult patients with severe renal dysfunction. Adult patients with conditions such as sepsis, multiple organ failure, or cardiac surgery complications benefit from CRRT as part of their comprehensive care.
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Europe is anticipated to witness significant growth in the CRRT market, driven by factors such as growing regulatory approvals in the European Union and a rising number of cases necessitating renal replacement therapy. A noteworthy example is a study published by Kidney Research UK in June 2023, forecasting an anticipated increase in AKI incidence in the UK from an estimated 615,000 episodes in 2022 to 637,000 by 2033. This growth underscores the evolving landscape of the European market and its pivotal role in the CRRT market.
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Competitive Landscape
The CRRT market is characterized by the presence of various small and big players. The major market player includes Asahi Kasei Medical, B. Braun, Baxter, Cytosorbents, Fresenius Medical Care, Infomed SA, Medtronic, Nikkiso, NIPRO, and Toray Medical amongst others. In a competitive market landscape, players are swiftly embracing advanced technologies to enhance CRRT operations and bolster their competitive stance through strategic initiatives, including mergers, acquisitions, and the introduction of new products.
For instance, in April 2022, Baxter International announced the US Food and Drug Administration 510(k) clearance for its ST Set designed for CRRT. Notably, it is actively utilized in Europe, Asia-Pacific, and North and South America, attesting to its global impact and widespread adoption across diverse healthcare settings.
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