ClinicalKey AI now includes full-text content from premium journals and medical organizations such as The Lancet, the New England Journal of Medicine (NEJM), the European Society For Medical Oncology and the American College of Cardiology, offering the broadest collection of trusted medical evidence-based content in a clinical AI solution
Elsevier has announced significant updates to ClinicalKey AI, its leading clinical decision support platform, introducing expanded content and technology improvements to meet the growing demands of clinicians for accuracy, transparency, and security in medical AI tools. Clinicians are working under increasing pressure with complex workloads, and while AI has potential to improve efficiency, trust remains a major concern. The adoption of AI in healthcare doubled in 2025, yet only 40 percent of clinicians reported confidence in these systems. The question is no longer whether AI can assist clinicians but whether it can be trusted.
Health Technology Insights: Ambience Healthcare Teams With MultiCare on AI Platform Rollout
ClinicalKey AI addresses this challenge by delivering evidence-based answers with complete traceability. The platform allows clinicians to see exactly which paragraph from which source was used to generate each response, providing full transparency and building confidence in the AI-generated information. The tool also incorporates a “clinician-in-the-loop” methodology to ensure quality and accuracy at every step.
The platform now includes full-text content and clinical practice guidelines from more than 1,000 peer-reviewed journals, including leading titles such as The Lancet, New England Journal of Medicine, Chest, Journal of Allergy and Clinical Immunology, Journal of Thoracic Oncology, and the American Journal of Obstetrics and Gynecology. ClinicalKey AI updates this content daily to ensure clinicians have access to the most current evidence. It also transforms the verified content into structured, linked data for precise and actionable insights in clinical practice.
Health Technology Insights: Integrity Health Cuts Costs 16 Percentage Using Lightbeam Health Platform
Joseph W. St. Geme III, MD, Physician-in-Chief at the Children’s Hospital of Philadelphia, stated that ClinicalKey AI provides highly reliable information that supports optimal patient management, citing references for transparency and enabling deeper exploration of literature. Dr. Vincenzo Defilippis, Head of the Quality and Safety Department at the Local Health Agency of Bari, Italy, highlighted that the updated version offers clinicians trusted intelligence drawn from the world’s largest evidence-based content set.
Elsevier has also improved the accessibility and usability of ClinicalKey AI. New features include API-based integration for workflow tools, a streamlined user interface, native voice-to-text functionality in the mobile app, query history controls, easy toggling between adult and pediatric contexts, multi-language support, and a privacy panel to ensure HIPAA compliance. A reading assistant is being added in March to facilitate learning and engagement with full-text articles.
Omry Bigger, President of Clinical Solutions at Elsevier, emphasized that these enhancements build on Elsevier’s 140-year legacy of trusted medical content. He explained that the upgrades respond to the daily challenges faced by clinicians, making ClinicalKey AI the most comprehensive and reliable clinical decision support platform available today. The combination of expanded full-text access, improved transparency, and advanced technology aims to give clinicians the confidence and tools they need to make informed decisions at the point of care.
Health Technology Insights: Lōkahi Therapeutics Welcomes UGA Fellows to ai² Futures Lab
To participate in our interviews, please write to our HealthTech Media Room at info@intentamplify.com
