Protection through 2039, ensuring long-term commercial exclusivity
Hoth Therapeutics, a clinical-stage biopharmaceutical company developing innovative therapies, announced that they have obtained Japan Country Patent No. 7677628 for the HT-KIT platform. The patent was officially granted by the Japan Patent Office on May 7, 2025, and exclusive protection is granted until August 27, 2039.
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The granted patent, titled “Targeting KIT with Splice Switching Oligonucleotides to Induce Apoptosis of Mast Cells,” protects Hoth’s novel approach of using splice-switching oligonucleotides to selectively disrupt KIT gene expression in mast cells—cells implicated in conditions ranging from chronic hives to rare cancers.
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“Securing intellectual property protection in Japan—a globally significant pharmaceutical market—underscores the global value of HT-KIT,” said Robb Knie, CEO of Hoth Therapeutics. “We see strategic licensing potential across Asia as we move this asset forward.”
Key Highlights
- Patent No. 7677628, granted by Japan Patent Office.
- Protection through 2039, ensuring long-term commercial exclusivity.
- Applicable to mast cell-driven inflammatory and oncologic conditions.
- Positioned for orphan indications and expedited regulatory pathways.
HT-KIT is one of several novel platforms under development at Hoth Therapeutics, which continues to seek strategic global partners, particularly in Asia, for co-development and commercialization opportunities.
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Source – PR Newswire